Endocrine Abstracts

LH receptor (LHR) is a G protein-coupled receptor (GPCR) that plays key roles in reproduction and pregnancy. Endocytic trafficking and sorting of GPCRs to diverse cellular fates represent a key mechanism in defining cellular responses by controlling both the temporal and spatial parameters of cellular signalling. How different processes within the endocytic system are coordinated, however, needs to be mechanistically dissected in more detail. We have recently demonstrated that...